Avermectin induced DNA damage to the apoptosis and autophagy in human lung epithelial A549 cells
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چکیده
منابع مشابه
AMPK is required for PM2.5-induced autophagy in human lung epithelial A549 cells.
The aim is to investigate the molecular mechanisms underlying the PM2.5-induced autophagy in human lung cancer epithelial cells (A549). The effects of the PM2.5 on morphological and biochemical markers of autophagy in A549 were analyzed by electron microscopy, GFP-LC3 puncta was observed by confocal fluorescence microscope. The effects of phosphorylation of AMPK, mTOR, AKT, ERK, JNK, and p53 on...
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ژورنال
عنوان ژورنال: Ecotoxicology and Environmental Safety
سال: 2021
ISSN: 0147-6513
DOI: 10.1016/j.ecoenv.2021.112129